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Genomics and Health Impact Blog Posts

Integrating Genomics into Public Health Surveillance: Ushering in a New Era of Precision Public Health

a crowd of people standing on sequincing and DNA and data graphs

Public health surveillance has been defined as “the ongoing systematic collection, analysis, and interpretation of data, closely integrated with the dissemination of these data to the public health practitioners, clinicians, and policy makers responsible for preventing and controlling disease and injury.” Surveillance provides an essential scientific foundation for both clinical and public health practice. In Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and PreventionLeave a commentTags

Whole Genome Sequencing for All? The Quest for Evidence Continues

a clinician holdig a stethoscope with DNA on the side

In 1999, Dr. Francis Collins predicted what the practice of genomic medicine in primary care may look like in 2010. He used a hypothetical patient named John, a 23-year-old man with high serum cholesterol. Based on his father’s history of early onset heart disease, John underwent a battery of genetic tests. He was found to Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention2 CommentsTags

Precision Public Health: Harnessing the Power of the Human Microbiome

four figures holding puzzle pieces standing on microbiome cells and DNA on the sides

The discovery of antibiotics by Sir Alexander Fleming in 1928 revolutionized medicine. However, antibiotics cannot differentiate between the beneficial bacteria that help keep us healthy and the pathogens that make us sick. Like a wildfire, antibiotics wipe out all bacteria. Consequently, we have been altering our microbiomes for almost a century, putting ourselves at risk Read More >

Posted on by Alison Laufer Halpin, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)3 CommentsTags

Are there any shortcuts on the translation highway to genomic medicine?

a long curved road with a curve caution sign and the road is paved with ATCG

Note to our readers: A modified version of this blog post has been published in JAMA. Rapid advances in genomics have led to a new era of precision medicine, resulting in a dramatic increase in the number of genomic tests available for research and clinical practice. As of April 18, 2017, the Genetic Testing Registry, Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention1 Comment

Genome Sequencing for Healthy Individuals? Think Big and Act Small!

a crowd of people with a magnifying glass on a few and DNA

In a 2013 blog post, we asked the question: “When should we all have our genomes sequenced?” At that time, we concluded that the time is not right and that “if we want to use whole genome sequencing in the course of regular preventive care and health promotion, research should be conducted to evaluate its Read More >

Posted on by Muin J. Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention, and Greg Feero, guest blogger, Maine Dartmouth Family Medicine ResidencyLeave a commentTags ,

Direct to Consumer Genetic Testing: Think Before You Spit, 2017 Edition!

test tubes and DNA

As people have become more proactive in managing their health, personal genomic direct to consumer (DTC) testing has become more popular over the past decade. These tests allow consumers to access information about genetic predispositions and response to chemicals and medications without the involvement of healthcare providers.  With the expanding landscape of such testing, the Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention5 CommentsTags ,

Genomics and Population Health Action: Join the Collaboration

a crowd forming two puzzle pieces coming togehter with DNA on the ground

In February 2017, I attended a one-day meeting of leaders of the Genomics and Population Health Action Collaborative (GPHAC). This group of more than 40 organizations and individuals is dedicated to the integration of genomics into clinical and public health programs to save lives and prevent disease. (Details on GPHAC and its membership can be Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and PreventionLeave a commentTags

Your Genes, Your Health: The Importance of Genetic Literacy and Education

a group of people from kinder garden to health professionals standing behind a table of building blocks made out of ATCG and the word GENES and DNA

In March 2017, the National Human Genome Research Institute, in collaboration with the Foundation for the NIH and several private sector organizations, held an important strategic planning meeting in Bethesda, the Genetic Literacy, Education and Empowerment (GLEE) Initiative. [PDF 415 KB] Advances in genomics over the past two decades are leading to opportunities to use Read More >

Posted on by Muin J. Khoury MD, PhD, Katherine Kolor, PHD, Office of Public Health Genomics, Centers for Disease Control and PreventionLeave a commentTags , ,

The need for a next-generation public health response to rare diseases.

a crowd of people in grey and one individual standing out in color and double helices on the border of the image

In recognition of Rare Disease Day 2017, we republish, with permission, a modified extract from our recent commentary in Genetics in Medicine. Few public health research activities trigger stronger calls to public health action than research into the burden of disease. This research uses standard measures to quantify actual or potential losses that populations may Read More >

Posted on by Rodolfo Valdez (guest blogger), Scott D. Grosse (guest blogger), National Center on Birth Defects and Developmental Disabilities & Muin J. Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention4 CommentsTags

Implementation Science in Genomic Medicine: Why we need it now!

DNA, a hand holding a test tube, electronic health record, a doctor talking to a girl and a person looking at data

With the launch of the precision medicine cohort initiative, All of UsSM  Research Program, the importance of incorporating implementation science in genomic medicine is greater than ever to ensure population health benefits for all. Historically, the speed of genomic discovery has far exceeded the time required to put these potentially life-saving medical discoveries into practice. Read More >

Posted on by Megan C. Roberts (guest blogger), David A. Chambers (guest blogger), Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, Maryland and Muin J. Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a commentTags , ,
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