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Category: pharmacogenomics

Integrating Pharmacogenomics in Practice: One GIFT at a Time or a Package Deal?

a present opened with DNA capsuls spilling out of them

Testing for genetic variants related to warfarin metabolism has been the poster child for pharmacogenomics in clinical practice for over a decade. A recent publication of the Genetic Informatics Trial (GIFT) provides additional evidence for the clinical benefits of incorporating pharmacogenomics testing into the management of warfarin initiation. In this multicenter study of older individuals Read More >

Posted on by W. Gregory Feero M.D., Ph.D. Faculty, Maine-Dartmouth Family Medicine Residency Program, Augusta, Maine and Muin J. Khoury, MD, PhD, Office of Public Health Genomics, Centers for Disease Control and PreventionLeave a commentTags , ,

Evidence Matters in Genomic Medicine- Round 4: Where are we with Pharmacogenomic Tests?

Previously, CDC’s Office of Public Health Genomics announced a list of health-related genomic tests and applications, stratified into three tiers according to the availability of scientific evidence and evidence-based recommendations and systematic reviews. The list is intended to promote information exchange and dialogue among researchers, providers, policy makers, and the public. Initially the table relied Read More >

Posted on by W. David Dotson, Michael P. Douglas and Katherine Kolor, Office of Public Health Genomics, Centers for Disease Control and PreventionLeave a commentTags , , ,

Medications for the Masses? Pharmacogenomics is an Important Public Health Issue

Adverse drug events are a serious public health problem. Consider the following facts: an estimated 82% of American adults take at least one medication and 29% take five or more; 700,000 emergency department visits and 120,000 hospitalizations are due to adverse drug events annually; $3.5 billion is spent on extra medical costs of adverse drug Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention3 CommentsTags , , ,
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