Category: public health

What is the Role of Public Health in Addressing Health Equity in Genomics and Precision Medicine?

a couple talking to a professional with a double helix

The following are excerpts from our recent paper in Genetics in Medicine. Although recent articles have included strong calls for a health equity agenda in genomics and precision medicine, these calls usually focus on underrepresentation of minority and ethnic populations in research.  However, to ensure that genomic discoveries can lead to improved population health outcomes, Read More >

Posted on by Muin J. Khoury, Office of Genomics and Precision Public Health, Office of Science, Centers for Disease Control and Prevention1 Comment
Categories genomics, precision medicine, public health

The Current Landscape of CDC Publications in Human Genomics and Public Health

sequencing with a double helix and a doctor pointing to different icons above a farm field

In October 2021, the CDC Office of Genomics and Precision Public Health (OGPPH) launched a new, five-year initiative to strengthen public health capacity in genomics and precision medicine. The emergence of evidence-based genomic applications and lack of equity in their implementation in clinical and public health practice provided an important impetus for this initiative. To Read More >

Posted on by Mindy Clyne, W. David Dotson, Anja Wulf, Muin J. Khoury, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a comment
Categories genomics, public health

An Expanding List of Tier 1 Genomic Applications: Evidence-based Guidelines for Hypertrophic Cardiomyopathy and Public Health

a heart in a body with the text: Tier 1 Genomic Applications

The CDC Tier-Classified Guideline Database includes three Tier 1 guidelines on hypertrophic cardiomyopathy (HCM). A 2014 guideline from the European Society of Cardiology, a 2017 guideline from the American Heart Association, American College of Cardiology, and Heart Rhythm Society, and a 2020 guideline from the American Heart Association and American College of Cardiology all recommend Read More >

Posted on by Michael A. Burke and Laurence S. Sperling, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia, W. David Dotson and Muin J. Khoury, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, Georgia1 Comment
Categories evidence-based medicine, public health
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What should be the public health priorities in genomics and precision medicine in the next decade?

Public Health Priorities for the next Decade with two figures looking at data with a double helix

The CDC Office of Genomics and Precision Public Health is undergoing strategic planning to identify major opportunities for impact of public health action in human genomics and precision medicine in the next decade. As part of this process, we interviewed nine persons external to CDC from diverse backgrounds and organizations that represent the leading edge Read More >

Posted on by Katherine Kolor, Ridgely Fisk Green, and Muin J. Khoury, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, Georgia1 Comment
Categories genomics, precision medicine, public health

What is Public Health Genomics? A Day in the Invisible Life of Public Health Genomics (an Encore)

Public Health Genomics with professionals looking at a double helix with a calendar

We published this blog a decade ago. As we celebrate 2021 public health genomics week, we republish the blog to remind our readers of the relevance of genomics to many areas of public health. The topics discussed  here may be outdated but the fundamental applications of public health genomics are today more important than ever. Read More >

Posted on by Muin J. Khoury, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a comment
Categories genomics, public health

Personal Reflections on Genomics, Health Equity, and Public Health

My nephew, Eddie, and niece, Sheri, were lively, witty, high-spirited, active, bright, and full of hope. Eddie dreamed of becoming a professional baseball player, while Sheri aspired to become a mathematical engineer. But their childhood diagnoses with a type of kidney disease called nephrotic syndrome ended those dreams. While nephrotic syndrome can be inherited, we Read More >

Posted on by Michelle Rose, Office of Science Scientific Rotation 2020–2021 cohort, and Ridgely Fisk Green, Office of Genomics and Precision Public HealthLeave a comment
Categories genomics, public health
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From Genes to Public Health: Building the Evidence Base for DNA-based Population Screening

sequencing with a double helix with figures in the foreground

This blog post is a summary of our recent commentary in Genetics in Medicine. The use of genetics in population screening long predates the Human Genome Project. For more than 60 years, newborn screening has been a successful public health program that has resulted in major improvements in outcomes for infants with genetic and other Read More >

Posted on by Muin J. Khoury MD, PhD, and W. David Dotson, PhD, Office of Genomics and Precision Public Health, Office of Science, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a comment
Categories genomics, Population screening, public health

Public Health Impact of Digital Health: Reinventing the Wheel

a cell phone being held by a stethoscope and a figure looking at the cell phone and thinking about reinventing the wheel

“Digital health has potential to improve health management, but the current state of technology development and deployment requires a “buyer beware” cautionary note.” (Perakslis and Ginsburg, JAMA, 2020) In a recent JAMA viewpoint, Perakslis and Ginsburg summarize the current state of digital health and discuss approaches in evaluating benefits, risks and value of these technologies. Read More >

Posted on by Muin J. Khoury and W. David Dotson, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a comment
Categories genomics, public health
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2020: A Challenging Year of Progress for Genomics and Precision Public Health

2020 with an arrow to 2021 with a double helix below and a COVID-19 virus and a masked family and under 2021 a person getting the COVID-19 vaccine

It is time to wrap up an eventful 2020 which unfortunately was dominated by the COVID-19 pandemic. From January 2020 through November 2020, we saw a major increase in visits to our website (> 2.6 million views, compared to 2 million views in 2019 and 1.2 million views in 2018). In our year end blog, Read More >

Posted on by Muin J. Khoury and Scott Bowen, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a comment
Categories family history, genomics, precision public health, public health
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A New Vision for Using Genomics to Improve Health: An Expanded Role for Public Health

four text box circles surrounding one circle in the middle with arrows pointing to: circle in the middle: Strategic vision, next circles: guiding principles and values, robust foundation for genomics, breaking down barriers that impede progress, compelling research projects

The National Human Genome Research Institute (NHGRI) recently published a new strategic vision 2020 to identify research priorities and opportunities in human genomics for improving health. The framework includes four main areas: guiding principles and values, a robust foundation for genomics, breaking down barriers that impede progress, and compelling research projects. Since the completion of Read More >

Posted on by Muin J. Khoury and W. David Dotson, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, Georgia1 Comment
Categories genomics, public health