Category: precision medicine

Genomics and Health Equity: Reaching Asian American, Native Hawaiian, and Pacific Islander Communities

On April 29, 2022, President Biden proclaimed May as Asian American, Native Hawaiian, and Pacific Islander Heritage month to “recognize the innumerable contributions, vibrant cultures, and rich heritage” of Asian Americans, Native Hawaiians, and Pacific Islanders (AA and NHPIs). In addition, the proclamation highlights the Administration’s work reducing poverty among AA and NHPI families and Read More >

Posted on by Zhuo (Adam) Chen, Katherine Kolor, and Ridgely Fisk Green, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, Georgia * Z Chen is an Associate Professor of Health Policy and Management at the University of Georgia and serves as a guest researcher with the Office of Genomics and Precision Public HealthLeave a commentTags

What is the Role of Public Health in Addressing Health Equity in Genomics and Precision Medicine?

a couple talking to a professional with a double helix

The following are excerpts from our recent paper in Genetics in Medicine. Although recent articles have included strong calls for a health equity agenda in genomics and precision medicine, these calls usually focus on underrepresentation of minority and ethnic populations in research.  However, to ensure that genomic discoveries can lead to improved population health outcomes, Read More >

Posted on by Muin J. Khoury, Office of Genomics and Precision Public Health, Office of Science, Centers for Disease Control and PreventionLeave a comment

From Precision Medicine to Precision Public Health: The Dialogue Continues

Precision on a triangle above Medicine and Public Health with the map of the US in the middle filled with a population and DNA and a magnifying glass on a person in red

A recent Nature article discusses the concept of precision public health (PPH) and raises concerns that too much emphasis on data and technology is “diverting attention away from regular public health.” In this post, we advance this important dialogue by focusing on two distinct components of PPH: its role in reaping the population health benefits Read More >

Posted on by Muin J. Khoury, Office of Genomics and Precision Public Health, Atlanta, Georgia, and Josh Denny, All of Us Research Program, National Institutes for Health, Bethesda, MarylandLeave a comment

What should be the public health priorities in genomics and precision medicine in the next decade?

Public Health Priorities for the next Decade with two figures looking at data with a double helix

The CDC Office of Genomics and Precision Public Health is undergoing strategic planning to identify major opportunities for impact of public health action in human genomics and precision medicine in the next decade. As part of this process, we interviewed nine persons external to CDC from diverse backgrounds and organizations that represent the leading edge Read More >

Posted on by Katherine Kolor, Ridgely Fisk Green, and Muin J. Khoury, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, Georgia1 Comment

Precision Medicine in Action: How can we make cascade screening for hereditary conditions work best in the real world?

a doctor looking at cascade screening

If someone in your family were diagnosed with a genetic condition, would you want to be tested for that condition as well? For some disorders, like Huntington’s disease, for which there are no means available for prevention or cure, the question can be extremely difficult to answer. However, with many other conditions (for example familial Read More >

Posted on by Swetha Srinivasan and Megan C. Roberts, Division of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill; Nae Yeon Won, Department of Orthopaedic Surgery, University of California, San Francisco; W. David Dotson and Muin J. Khoury, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a commentTags

Predictive Analytics, Implementation Science, Precision Medicine and Precision Public Health

twp figures looking at a wall of graphs depicting predicive analytics, a doctor with a stethoscope that has a magifying glass on a red figure surrounded by lots of other clusters of figures

This blog is a summary of our recent paper based on a multidisciplinary workshop convened by the National Heart, Lung, and Blood Institute to explore enhancement of predictive analytics for implementation research. The use of predictive analytics in precision medicine (the right intervention to the right patient at the right time) is well established. The Read More >

Posted on by Muin J. Khoury and George A. Mensah *Leave a commentTags ,

From Precision Medicine to Precision Public Health: Beyond the Pandemic

the word Medicine with an arrow to the word Public Health and the word Precision over all of them with a background of connected people and several COVID-19 viruses

Precision medicine and precision public health are emerging fields that use genomics and other big data technologies to provide more targeted interventions at the individual and population levels. Precision medicine can be thought of as delivering the right intervention to the right individual at the right time, while precision public health can be simply viewed Read More >

Posted on by Muin J. Khoury, Office of Genomics and Precision Public Health, and Michael F. Iademarco, Center for Epidemiology, Surveillance and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a commentTags

A 2020 Reality Check on the Public Health Impact of Cancer Genomics and Precision Medicine

cancer cells with DNA and a crowd of people running and fresh fruits and vegetables

“Precision oncology has had some major successes… And yet, the overall effect of precision medicine on care for patients with cancer has been modest.” (David Cutler, JAMA Health Forum, 2020) The Promise of Genomics and Precision Medicine in Reducing the Burden of Cancer In 2015, the United States launched the Precision Medicine Initiative (PMI) “to Read More >

Posted on by Muin J. Khoury, Office of Genomics and Precision Public Health, Office of Science and Juan Rodriguez, Division of Cancer Prevention and Control, National Center on Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a comment

Precision Medicine Update: Important Progress on the Long Road from Discovery to Population Health Impact

a long road with DNA and the text Discovery and Population Health Impact

Impressive Pace and Potential The All of Us Research Program is an ambitious United States initiative launched in 2015 to collect health-related information on one million or more volunteers from diverse communities. A recent paper in the New England Journal of Medicine described progress and lays out the vision for the initiative moving forward. As Read More >

Posted on by Muin J. Khoury, Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta Georgia and George A. Mensah, Center for Translation Research and Implementation Science, National Heart, Lung, and Blood InstituteLeave a commentTags

Why should early career public health researchers pay attention to precision medicine?

one main figure connect to three others

In a recent commentary published in the American Journal of Public Health, I had the privilege of working with a group of early career investigators to begin a conversation about the impact that the debate between the utility of precision medicine and public health approaches is having as we begin our research careers. To begin, let’s Read More >

Posted on by Caitlin G. Allen, MPH, Doctoral Student, Behavioral Sciences and Health Education Department, Emory University Rollins School of Public Health, Atlanta, GeorgiaLeave a commentTags