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Category: genomics

More Workings of an Evidence-Based Genomic Panel: Modernizing the Evidence Review Process

EGAPP logo

The independent EGAPP working group (EWG) held its 25th meeting on September 10-11, 2012 at the CDC campus in Atlanta. Highlights included: Three EWG recommendation statements on the validity and utility of genetic tests are pending publication on: KRAS, BRAF and other markers involved in EGFR signaling, which are used to inform choice of therapies for Read More >

Posted on by W. David Dotson and Michael P. Douglas, Office of Public Health Genomics, Centers for Disease Control and PreventionLeave a commentTags ,

What Gets Measured Gets Done: Genomics, Surveillance Indicators and Healthy People 2020

graph

Public health surveillance indicators, such as those developed for the Healthy People initiative are useful for monitoring the development of genomic medicine in the United States. For several decades, Healthy People has established health benchmarks that are considered important metrics for tracking progress in health and healthcare in the United States. Read More >

Posted on by Muin J Khoury and Katherine Kolor, Office of Public Health Genomics, Centers for Disease Control and PreventionLeave a commentTags , , ,

Now Watch This: Genomic Epidemiology

Staphylococcus aureus bacteria

Late last year, Science magazine published a list of six Areas to Watch in 2012. Number 6 on the list, NASA’s Curiosity rover, recently touched down on Mars. The Higgs boson (#1) has been found, faster-than-light neutrinos (#2) have been debunked, and further developments on stem-cell metabolism (#3) and treatments for intellectual disability (#5) are Read More >

Posted on by Marta Gwinn, Consultant, McKing Consulting Corp, Office of Public Health Genomics, Centers for Disease Control and PreventionLeave a commentTags ,

Evidence Matters in Genomic Medicine- Round 2: Integrating Cancer Genomic Tests

stacked boxes with lettering

  In a previous blog, CDC’s Office of Public Health Genomics announced a list of health-related genomic tests and applications, stratified into three tiers according to the availability of scientific evidence and evidence-based recommendations as a result of systematic reviews.  The list is intended to promote information exchange and dialogue among researchers, providers, policy makers, and Read More >

Posted on by Michael P. Douglas and W. David Dotson, Office of Public Health Genomics, Centers for Disease Control and Prevention1 CommentTags , , ,

Think After You Spit: Personal Genomic Tests May Offer a Teachable Moment

Patient is showing physician her DTC genetic test results

Personal genomic tests are now widely available and sold directly to consumers, but population-based data are limited on awareness, use and impact of these tests. In collaboration with 4 state public health genomics programs, we have recently reported  on consumer awareness and use of personal genomic tests using the 2009 Behavioral Risk Factor Surveillance System. Read More >

Posted on by Muin J Khoury and Katherine Kolor, Office of Public Health Genomics, Centers for Disease Control and Prevention1 CommentTags , , ,

Peeling the Pyramid, Scaling the Onion—How to Implement Genomic Medicine

pyramid of onion slices

In spite of the promise of genomics and related technologies for a new era of precision healthcare and disease prevention, only a handful of genomic tests and applications have been recommended for use in clinical practice. Nevertheless, implementation of even the few recommended genomic tests is lagging.  For example, implementing the 2005 USPSTF recommendation on genetic Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and PreventionLeave a commentTags , , ,

Workings of an Evidence-Based Genomic Panel

EGAPP logo

  Synopsis of the 24th Meeting of the Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group The EGAPP working group (EWG) has held 24 meetings in the 7 years since they were first convened; the latest EGAPP meeting was May 7-8, 2012 on the campus of CDC in Atlanta. Since it is Read More >

Posted on by W. David Dotson and Michael P. Douglas, Office of Public Health Genomics, Centers for Disease Control and PreventionLeave a commentTags , , , , , ,

Sharing the Burden of Obesity

world globe balanced on top of a scale including a DNA strand as the equator

  On May 7-9, the CDC Division of Nutrition, Physical Activity, and Obesity, hosted a conference on Weight of the Nation™ in Washington, D.C.  The conference served to highlight progress in the prevention and control of obesity through policy and environmental strategies. The­ Weight of the Nation is also the title of an HBO Documentary Read More >

Posted on by Marta Gwinn, Consultant, McKing Consulting Corp, Office of Public Health Genomics, Centers for Disease Control and Prevention1 CommentTags , , , ,

Genomic Tests and Population Health: An Online Catalog to Promote a Conversation on Evolving Evidence

stacked boxed with A T C G on them

  With the rapid emergence of genomic tests, healthcare providers, patients and policy makers need to know how useful they are and whether the benefits of their use outweigh potential harms to patients, families, and the population. CDC’s Office of Public Health Genomics now offers a list of health-related genomic tests and applications, stratified into Read More >

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention4 CommentsTags , , , , ,

Smoke Screen…

  Never Let Genetics Blind You to the Harsh Reality of Cigarettes The emerging field of genomics might one day provide some tools to help address the smoking epidemic.  However, smokers should never think that their genes can protect them from devastating harms or provide an easy way for them to quit later. In 2012, Read More >

Posted on by Scott Bowen, Office of Public Health Genomics, Centers For Disease Control and PreventionLeave a commentTags , , ,
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