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10 results for colorectal cancer

How Common is Familial Hypercholesterolemia?

people holding hands with a heart above them in the air

Familial Hypercholesterolemia (FH) is a genetic condition that leads to high blood levels of low-density lipoprotein cholesterol, also known as LDL-C or “bad cholesterol.” Most people with FH have heterozygous FH, meaning they have only one FH-causing mutation, but in rare cases, a person can have homozygous FH, meaning they have FH-causing mutations in both

Posted on by Frank Swann, Dual MSGC/MPH Class of 2022, University of Pittsburgh Graduate School of Public Health and Ridgely Fisk Green, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention
Categories genomics
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Precision Medicine in Action: How can we make cascade screening for hereditary conditions work best in the real world?

a doctor looking at cascade screening

If someone in your family were diagnosed with a genetic condition, would you want to be tested for that condition as well? For some disorders, like Huntington’s disease, for which there are no means available for prevention or cure, the question can be extremely difficult to answer. However, with many other conditions (for example familial

Posted on by Swetha Srinivasan and Megan C. Roberts, Division of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill; Nae Yeon Won, Department of Orthopaedic Surgery, University of California, San Francisco; W. David Dotson and Muin J. Khoury, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, Georgia
Categories genomics, precision medicine
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The Long Road to Population-based Genomic Screening

Since 2012, the CDC Office of Genomics and Precision Public Health (OGPPH) has identified three autosomal dominant conditions for which there exist evidence-based recommendations to prevent morbidity and mortality from either cancer or heart disease. Using our evidence-based framework, we have collectively labeled the following conditions as tier 1 genomic applications: 1) hereditary breast and

Posted on by Muin J. Khoury, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, Georgia and Michael F. Murray, Clinical director, Center for Genomic Medicine, Yale University School of Medicine, New Haven, Connecticut3 Comments
Categories genomics, Population screening, screening

Communication and Information Sharing about Genomics and Precision Health: Opportunities for Improvement

several hands holding puzzle pieces labeled PHGKb, Genomic Blog, Twitter Posts, Weekly Update, Tiered Evidence, an image of a bullhorn, three people conversing and a magnifying glass. These puzzle pieces are being pushed together to a center piece in red with DNA.

In this blog, we describe our current approach to information sharing based on a recent review of our communication and engagement strategies. In order to improve our approaches to communication, we are asking you, our readers, for feedback—please share your thoughts in the comments section below or send us an email at mailto:genetics@cdc.gov. For the

Posted on by Caitlin G. Allen, Ridgely Fisk Green and Muin J. Khoury, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, Georgia
Categories genomics
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Happy Thanksgiving 2019: Collect and Share Your Family Health History: It Could Save Your Life!

a multi generational family sharing a Thanksgiving meal

Happy Thanksgiving Day! It is time for our yearly message on the importance of family health history to your own health. Year after year we promote the value on family health history around Thanksgiving day and all year round. By knowing and acting on your family history, you can reduce your disease risk and actually

Posted on by Muin J Khoury, Director, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention
Categories family history, genomics

How Genetic Counselors are Dealing with Direct-to-Consumer Genetic Testing

a genetic counselor talking to a client with DNA in the background

After receiving ancestry information from a direct-to-consumer (DTC) genetic testing company, Ellen Matloff, a certified genetic counselor and frequent writer about the limitations of DTC tests, downloaded her raw data file from their website for interpretation by a third party service. She was shocked to see that her raw data included a variant for Lynch

Posted on by Suzy Cahn, Guest Blogger, Genetic Counseling Training Program Class of 2019, Emory University School of Medicine and Ridgely Fisk Green, Office of Public Health Genomics, Centers for Disease Control and Prevention
Categories genetic counseling, genomics, personal genomics

Happy Thanksgiving 2018: Protect your family’s health by using My Family Health Portrait to collect and share your family health history

a multigenerational familly eating a thanksgiving meal and a picture of DNA is hanging on the wall

Happy Thanksgiving Day! It is time to send our yearly message on the importance of family health history to your own health. Every year we emphasize a slightly different version of this message. In 2017, we highlighted the simple fact that even in the age of genomics and precision medicine, family health history remains as

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention
Categories family history, genomics
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Happy Thanksgiving 2017: Take time to collect, share, and act on your family health history, it may save your life!

Happy Thanksgiving 2017 with an image of DNA and pumpkins and leaves

Regular readers of this blog may have noticed that we have an almost identical message around each Thanksgiving Day. Collect, share, and act on your family health history! It seems every year we emphasize a slightly different version of this message. In 2016, we highlighted the emergence of new tools that can help consumers and

Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention
Categories family history, genomics

Implementing Evidence-based Genomics Recommendations at the Intersection of Public Health and Healthcare

several publications from Michigan

We take the opportunity of March 22, 2013, designated as Lynch Syndrome Awareness Day by 13 U.S. state governors and counting, to highlight state public health genomics programs that are taking innovative approaches to implement evidence-based genomic testing recommendations for hereditary cancer syndromes, including Lynch syndrome. 

Posted on by Jenna McLosky and Debra Duquette, Michigan Department of Community Health Beverly Burke and Joan Foland, Connecticut Department of Public Health
Categories evidence-based medicine, genomics, public health
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New Strategies For Public Health Genomics Beyond Newborn Screening

Opening speaker, Dr. Ursula Bauer Director, NCCDPHP discusses a point later in the day with Dr. Khoury, OPHG Director

A Working Meeting and an Action Plan to Save Lives Now Nearly 2 million Americans are affected by one of three genetic conditions with a strong risk of early morbidity and mortality: BRCA 1/2 and hereditary breast and ovarian cancer; Lynch syndrome and colorectal , endometrial and ovarian cancer; and familial hypercholesterolemia and early cardiovascular events.  At

Posted on by Scott Bowen and Karen Greendale, Office of Public Health Genomics, Centers For Disease Control and Prevention2 Comments
Categories evidence-based medicine, family history, genomics, public health
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