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Predictive Analytics, Implementation Science, Precision Medicine and Precision Public Health
This blog is a summary of our recent paper based on a multidisciplinary workshop convened by the National Heart, Lung, and Blood Institute to explore enhancement of predictive analytics for implementation research. The use of predictive analytics in precision medicine (the right intervention to the right patient at the right time) is well established. The
Posted on by Leave a commentFrom Precision Medicine to Precision Public Health: Beyond the Pandemic
Precision medicine and precision public health are emerging fields that use genomics and other big data technologies to provide more targeted interventions at the individual and population levels. Precision medicine can be thought of as delivering the right intervention to the right individual at the right time, while precision public health can be simply viewed
Posted on by Leave a commentImplementation Science to Improve Case Finding, Cascade Screening, and Treatment for Familial Hypercholesterolemia: A Prototype for Precision Public Health Research
Familial Hypercholesterolemia (FH) is a common genetic disorder, affecting more than 1 million people in the United States. FH causes lifelong high levels of low-density lipoprotein cholesterol, and if untreated, leads to a high risk of premature coronary heart disease. Most patients with FH are undiagnosed or inadequately treated with regular or high-intensity statins, leaving
Posted on by Leave a commentUsing Digital Technologies in Precision Public Health: COVID-19 and Beyond
With the global spread of COVID-19, there is a proliferation of scientific information and publications that use novel approaches such as genomics and precision health tools (e.g., big data, wearables, and digital devices) in surveillance and epidemiologic investigations. Could these new technologies provide added value to traditional approaches? In the past, we have written about
Posted on by Leave a commentManipulating the Human Microbiome for Precision Public Health: Prospects and Challenges
Spotlight on the Human Microbiome The human microbiome has a crucial role in driving public health science and initiatives towards more “precision”. In a recent viewpoint and podcast, Harkins, et al. discuss the potential and current applications for manipulating the human microbiome for disease prevention and management. The authors describe several examples of microbiome manipulation
Posted on by Leave a commentProgress in Pathogen Genomics as a Prototype for Precision Public Health
Rapid advances in pathogen genomics have ushered in a new era of “precision public health.” Next-generation sequencing is already enabling more effective investigations of outbreaks of foodborne illnesses, better-targeted tuberculosis control, and more timely and granular influenza surveillance to inform the selection of vaccine strains. In a recent paper in the New England Journal of
Posted on by Leave a commentFamilial Hypercholesterolemia as a Prototype for Precision Public Health
In October 2019, the 7th annual FH Foundation global summit on familial hypercholesterolemia (FH) took place in Atlanta, Georgia. The theme of the conference was, “Familial Hypercholesterolemia as a Prototype for Precision Public Health.” The meeting brought more than 300 participants from multiple countries to discuss the latest advances in the diagnosis, screening, treatment and
Posted on by Leave a commentIntroducing the CDC Office of Genomics and Precision Public Health: What’s in a Name?
Starting this week, the CDC Office of Public Health Genomics will be renamed the CDC Office of Genomics and Precision Public Health. In many ways, this transition has been a few years in the making and reflects the continuous broadening of our scope from human genomics and public health to include other areas relevant to
Posted on by Leave a commentCan Big Data Science Deliver Precision Public Health?
This blog is a quick summary of our recent paper in Public Health Genomics. Increasingly, a large volume of health and non-health related data from multiple sources is becoming available that has the potential to drive health related discoveries and implementation. The term “big data” is often used as a buzzword to refer to large
Posted on by Leave a commentPrecision Public Health: What Is It?
In the past two years the term “precision public health” has been increasingly used in the scientific literature and at professional meetings. A quick PubMed search of the term shows 28 papers (as of April 30, 2018) dating back to our 2016 paper, “Precision Public Health for the Era of Precision Medicine.” The papers cover
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