Occupational Exposures to New Drycleaning Solvents

Posted on by Diana Ceballos, PhD, MS, CIH; Stephen Whittaker, PhD; and Eun Gyung Lee, PhD, CIH
Employee pressing shirts by using two pressing machines.
Employee pressing shirts by using two pressing machines in series.


There are about 36,000 commercial drycleaning shops in the United States. Most are owner-operated small businesses with fewer than 10 employees. In addition, some drycleaning shops may be owned and staffed by individuals with limited English language skills and/or may be marginally profitable– factors that may create additional barriers for the owner-operator to maintain a safe and healthy workplace.

Drycleaning Solvents

Environmental regulatory requirements and an increased awareness of the potential occupational hazards from using the drycleaning chemical perchloroethylene (PERC) have resulted in some drycleaners switching to alternative chemicals. Some of the PERC alternatives are promoted as safe and environmentally friendly, although their effects on human health and the environment are not well characterized. Some of the alternative drycleaning agents include:

  • 1-bromopropane; (see blog 1-Bromopropane)
  • high-flashpoint hydrocarbons;
  • butylal;
  • liquid silicone;
  • dipropylene glycol t-butyl ether; and
  • glycol ether cleaning liquid with liquid carbon dioxide.

Additionally, professional wet washing using water and detergents has also been used along with or to replace solvent-based drycleaning [EPA 2015].

Evaluating Employees Exposures to New Drycleaning Solvents

In 2012, investigators from the National Institute for Occupational Safety and Health (NIOSH) began working  with the Local Hazardous Waste Management Program in King County, Washington (LHWMP)* to learn about occupational exposures to two alternative solvents. We performed four Health Hazard Evaluations at drycleaners that used either a high-flashpoint hydrocarbon mixture or butylal.

We collected personal and area air samples for the drycleaning solvents, as well as for formaldehyde and butanol, which are potential hydrolysis byproducts of butylal. We learned that the highest air concentrations of the drycleaning solvents were during loading and unloading of the machines and when pressing fabrics. Concentrations of the high-flashpoint hydrocarbon mixture and butanol in air were well below occupational exposure limits. However, there are no occupational exposure limits for butylal, and the long-term human health effects of butylal are unknown. We used control banding tools to assist in developing control recommendations for this solvent. When measuring for the other byproduct of butylal, formaldehyde, we did not find measurable levels or found very low concentrations in the air. The shop owners added a manufacturer recommended neutralizer to the drycleaning machine using butylal that helps prevent hydrolysis of the solvent and release of formaldehyde and butanol.

Because exposure to these drycleaning solvents can occur through skin contact, we also took surface patch samples on two employees to see if they were getting these solvents on their hands during the machine cleaning process despite wearing gloves. We found solvents on their hands that may have resulted from reusing gloves or not selecting the proper glove material.

We saw employees mixing the butylal-based solvent with a fabric pretreatment and spraying the spot treatment mixture without personal protective equipment (such as gloves and eye protection). We also saw employees cleaning the waste material from the drycleaning machines without adequate personal protective equipment.

We provided recommendations for the shop owners and employees to help reduce their exposures to the drycleaning solvents and other chemicals. The recommendations involved work practice changes, improved housekeeping, equipment maintenance, and the proper selection and use of personal protective equipment. We also recommended employees brush and not spray fabric spot treatments, and wear eye and skin protection when cleaning the waste material from drycleaning machines. These recommendations were consistent with those resulting from our control banding assessment for butylal. See the reports below for complete prevention guidelines.

These evaluations are one step towards understanding the risks involved with alternative drycleaning solvents. Further research is needed to investigate the long term health effects of butylal. Independent evaluation of the toxicological properties of these alternative drycleaning solvents is needed.

For more information, see NIOSH Health Hazard Evaluations:

Help Wanted

We would like to hear from you.  In the comment section below, please  let us know:

  • What other new drycleaning solvents are being used to replace PERC?
  • Are airborne or skin exposures to new dry cleaning agents being measured in your workplace?
  • Are employees experiencing any health concerns that you think may be associated with the use of new drycleaning solvents?

We would also like to conduct more Health Hazard Evaluations in drycleaning establishments that use alternatives to PERC. If you are interested, you can request an HHE at our website. We can also provide technical assistance on requests to states and other government organizations that may be interested in improving the health and safety climate in the drycleaning industry.


Diana Ceballos, PhD, MS, CIH  is an Industrial Hygienist in the NIOSH Hazard Evaluations and Technical Assistance Branch in the Division of Surveillance, Hazard Evaluations and Field Studies.

Stephen Whittaker, PhD is with the Local Hazardous Waste Management Program in King County, Washington.

Eun Gyung Lee, PhD, CIH is an Industrial Hygienist in the Exposure Assessment Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health.



California Environmental Protection Agency, Air Resource Board, drycleaning program webpage

Environmental Protection Agency (EPA), case study: wetcleaning systems for garment care webpage

Local Hazardous Waste Management Program in King County, Washington drycleaning webpage

New York State, Department of Environmental Conservation, approved alternative solvents for drycleaning webpage

Toxic Use Reduction Institute (TURI), UMASS Lowell, drycleaning webpage

TURI, PERC Alternatives Assessment Fact Sheet


*LHWMP is a coalition of local governments with the mission to protect and enhance public health and environmental quality in King County, Washington by reducing the threat posed by the production, use, storage and disposal of hazardous materials

Posted on by Diana Ceballos, PhD, MS, CIH; Stephen Whittaker, PhD; and Eun Gyung Lee, PhD, CIH

14 comments on “Occupational Exposures to New Drycleaning Solvents”

Comments listed below are posted by individuals not associated with CDC, unless otherwise stated. These comments do not represent the official views of CDC, and CDC does not guarantee that any information posted by individuals on this site is correct, and disclaims any liability for any loss or damage resulting from reliance on any such information. Read more about our comment policy ».

    Have there been studies of residuals left on the clothing subjected to these chemicals and the long term effects to the wearers of these garments?

    NIOSH research focuses on worker exposure, so we have conducted no studies of exposure to customers who wear clothing treated with the PERC-alternative chemicals. However a search of the literature shows that some researchers have examined this issue for PERC (we are not aware of any studies on the alternatives). For example see, “Emissions of perchloroethylene from dry cleaned fabrics,” by Bruce A. Tichenor, et.al, Atmospheric Environment, v 24, No 5, pp 1219-1229 (1990); See: http://www.sciencedirect.com/science/article/pii/0960168690900874. We should note that our studies, once published, become part of the scientific literature that can be used by others who have authority and responsibility for environmental and consumer exposures.

    Workers expsure may be minimised by good ventilation.
    Any garment dry-cleaned will not be completely free of the solvents. It is, therefore, advisable that the user of such a garment exposes the garment to open air for some time before donning it. I am writing this out of my own experience. Such an exposure certainly reduces the contamination. “Smell reduction” is a measure of the contamination, if any.

    K.N.Krishna Prasad
    Chartered enginer; ESH consultant and Trainer.

    I’ve been in the dry cleaning industry over fifty years. At one time I had nine locations and seventy employees but when I had my first two cancers I eliminated the slower locations. Earlier I opened many stores myself and did all the dry cleaning and this was my main exposures. My three cancers were colon stage 4, bladder cancers that were removed easily and then base of tongue stage 4. I have been a professional wet cleaner now for 12 years with one good location and we process ALL garments. All our spotting solutions and our cleaning solutions are approved by the EPA.

    I think all dry cleaners should be required to post, in the lobby, what solvents (or water) they are using as well as all the types of hazardous waste they generate.

    Further more I believe it is possible to completely ELIMINATE ALL HAZARDOUS WASTE from dry cleaners in the state of California.

    I will soon have a power point presentation that I will be offering to the public and service clubs in my area explaining everything I have said here.

    As I said earlier we process ALL garments regardless of the care labels and fabric content. If all dry cleaners became “Garment Cleaners then Wet Cleaning would eliminate all hazardous waste.

    Contact me if you are interested in my power point presentation and learning about how I process all garments without hazardous waste.
    Steve Berglund
    Mastercraft Natural Cleaning
    Fresno CA
    Office 559 224-3113

    I’ve read a bunch of articles for my research about the effects of dry cleaning on the health of the workers on the said industry. Yes, there’s no doubt that without seeing through the precautionary measures may actually cause bad effects. But nevertheless, employees and companies themselves should see to it that their workers are well taken care of because it’ll be ironic how they take care when it comes to the clothes that should be dry clean, but can’t implement it within themselves. Also, there are eco-friendly detergents that have been popularly use globally.

    The effects of prolonged or repeated exposure are: dermatitis, central nervous system (headache, difficulty concentrating) and impaired liver function.

    Now a days dry cleaning is very essential in our dally life. It is an informative article on this. Thanks for sharing.

    Nice post for Dry cleaners!!!!! I really like it and appreciate also. It is very informative blog. Keep sharing more post like this. Thanks for updating good post.

    Great post for the people who are engaged in this dry cleaning industry. Not only for them but also for the seekers who want to know what kind of solvents are used in dry cleaning. This evolution is very inspiring how the solvents are tested and after full analysis they are used.

    People who are engaged in dry cleaning industry use these dry cleaning solvents. It is very necessary to have certain precautions while dealing with these solvents. This post gave us some proper knowledge about the how solvents can be used in various fields. Thanks a lot.

    Nice Post!!!!Your blog about dry cleaning is very nice. This article is also very good. I love it.This is very interesting blog. I really like it, Keep sharing more post like this.Thanks for the great hints.

    To find cleaning services are now very easy. Your blog is very helpful and informative. Your tips are really wonderful. Thanks for providing us with information regarding this topic.

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Page last reviewed: May 24, 2017
Page last updated: May 24, 2017