Genomics and Precision Health Posts
Why We Can’t Wait: A Public Health Approach to Health Disparities in Genomic Medicine
In May 2013, I attended and presented at the “Why We Can’t Wait Conference to Eliminate Health Disparities in Genomic Medicine.” The conference was organized by the University of Miami and Stanford University, with attendees and speakers from academia, consumer organizations, government agencies, public health, clinical practice, and the private sector. A key rationale for Read More >
Posted on byA Public Health Genomic State-by-State Clickable Map: Accelerating Implementation of Genomics Applications to Improve Population Health
In recent years, public health programs in several states have used innovative approaches to implement evidence-based genomic testing recommendations in an effort to improve health outcomes for people at increased hereditary risk for breast, ovarian, colorectal and other cancers. For example, the Michigan Department of Community Health [PDF 1.04 MB] has partnered with payers in Read More >
Posted on by 1 CommentNew Products from the EGAPP Working Group: Further Development of Evidence Review Methodology and More Recommendations in Genomic Medicine
The independent EGAPP working group (EWG) held its 27th meeting on May 13-14, 2013 via a virtual online venue. The EWG has been very active since the last meeting. Highlights included: The EWG has four new publications since the last meeting: Recommendations from the EGAPP Working Group: does genomic profiling to assess type 2 diabetes Read More >
Posted on byGenomes at CDC: Man, Mouse, and Microbe—it’s a Genomic World
The proposed Advanced Molecular Detection initiative aims to help CDC apply molecular sequencing and bioinformatics techniques to solving outbreaks and controlling infectious diseases. This approach has been called “genomic epidemiology”—using pathogen genome sequences to detect emerging diseases, assess their potential virulence and resistance to antibiotics, and monitor their spread in populations. The focus is on Read More >
Posted on byWalking Before Running: Genomic Medicine 10 Years After the Human Genome Project
It has been said that the folks at the National Human Genome Research Institute (NHGRI) never pass up the chance for well-deserved celebration – and I should know, I was one of them. Probably at least a few readers have noticed that the Human Genome Project (HGP) has celebrated a number of milestones and anniversaries over Read More >
Posted on by 1 CommentOn Spinning Wheels and Genomes Revealed:
Sequencing is No Longer a Sleeping Controversy In the classic Disney version of the fairy tale, Sleeping Beauty is hidden in the woods to protect her from the knowledge of an evil curse… but when she later pricks her finger on a spinning wheel, she falls under a fairy’s spell… Unlike the mythical magic of Read More >
Posted on byImplementing Evidence-based Genomics Recommendations at the Intersection of Public Health and Healthcare
We take the opportunity of March 22, 2013, designated as Lynch Syndrome Awareness Day by 13 U.S. state governors and counting, to highlight state public health genomics programs that are taking innovative approaches to implement evidence-based genomic testing recommendations for hereditary cancer syndromes, including Lynch syndrome. Read More >
Posted on byAccelerating the Development of Evidence Reviews and Recommendations in Genomic Medicine
The independent EGAPP working group (EWG) held its 26th meeting on February 11-12, 2013 at the CDC campus in Atlanta. Highlights included: Three EWG recommendation statements on the validity and utility of genetic tests are pending publication on: KRAS, BRAF and other markers involved in EGFR signaling, which are used to inform choice of therapies for Read More >
Posted on byHow Can We Use Genetic Testing in Population Screening for Common Diseases?
Scientific and implementation challenges Population screening for disease is a concept that has been around for many decades. Its main purpose is early detection and treatment of asymptomatic disease, or risk assessment and prevention of future disease, in order to improve health outcomes in individuals and populations. Examples include mammography in breast cancer screening and Read More >
Posted on by 1 CommentWhat’s the Connection Between Polio Eradication and Primary Immunodeficiency?
A Public Health Role for Human Genetics Two non-profit foundations with distinct missions recently announced that they are joining forces to support polio eradication. The Bill & Melinda Gates Foundation (BMGF) supports global health programs; the Jeffrey Modell Foundation (JMF) advocates for early diagnosis and treatment of genetic immunodeficiency disorders. How did these organizations find common Read More >
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