Category: precision public health

From Precision Medicine to Precision Public Health: Beyond the Pandemic

the word Medicine with an arrow to the word Public Health and the word Precision over all of them with a background of connected people and several COVID-19 viruses

Precision medicine and precision public health are emerging fields that use genomics and other big data technologies to provide more targeted interventions at the individual and population levels. Precision medicine can be thought of as delivering the right intervention to the right individual at the right time, while precision public health can be simply viewed Read More >

Posted on by Muin J. Khoury, Office of Genomics and Precision Public Health, and Michael F. Iademarco, Center for Epidemiology, Surveillance and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a commentTags

Accelerating Precision in Public Health Surveillance and Response

When our communities face a health crisis, the research, clinical, and public health worlds come together and collaborate. Public health programs drive toward prevention, diagnosis, and treatment of the population, but they need the support and guidance of data-driven research behind them every step of the way. While most of the data needed to accelerate Read More >

Posted on by Paula Braun (CDC), Kevin Chaney (ONC), Muin J. Khoury (CDC), Teresa Zayas Cabán (ONC)Leave a commentTags

Using Digital Technologies in Precision Public Health: COVID-19 and Beyond

a hand holdign a cell phone with lots of data surrounding it including a coronavirus cell

With the global spread of COVID-19, there is a proliferation of scientific information and publications that use novel approaches such as genomics and precision health tools (e.g., big data, wearables, and digital devices) in surveillance and epidemiologic investigations. Could these new technologies provide added value to traditional approaches? In the past, we have written about Read More >

Posted on by Muin J. Khoury, Scott Bowen, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, Georgia; Paula Braun, Entrepreneur in Residence, Centers for Disease Control and PreventionLeave a commentTags ,

Manipulating the Human Microbiome for Precision Public Health: Prospects and Challenges

a body with different external influences surrounding it

Spotlight on the Human Microbiome The human microbiome has a crucial role in driving public health science and initiatives towards more “precision”. In a recent viewpoint and podcast, Harkins, et al. discuss the potential and current applications for manipulating the human microbiome for disease prevention and management. The authors describe several examples of microbiome manipulation Read More >

Posted on by Melia Haile, Alison Laufer Halpin, Christopher Elkins, and Clifford McDonald, Division of Healthcare Quality Promotion, NCEZID; Muin J. Khoury, Office of Genomics and Precision Public Health, Office of Science, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a commentTags

In the Era of Public Health Emergencies, Interoperability Rules are a Beacon for More Precision in Public Health

In the current wake of COVID-19, it is evident that the public health ecosystem needs to modernize how we gather, make sense of, and disseminate data from multiple sources.  The health threats we face today spread wider and change faster than the data flows our traditional approaches were designed to accommodate.  Becoming more adept with Read More >

Posted on by Paula Braun, Entrepreneur in Residence, Centers for Disease Control and PreventionLeave a comment

Progress in Pathogen Genomics as a Prototype for Precision Public Health

four arrows labeled Bacterial Foodborne Illness, Parasitic Diseases, Tuberculosis and Influenza pointing to Pathogen Genomics: A Prototype for Precision Public Health with DNA around

Rapid advances in pathogen genomics have ushered in a new era of “precision public health.” Next-generation sequencing is already enabling more effective investigations of outbreaks of foodborne illnesses, better-targeted tuberculosis control, and more timely and granular influenza surveillance to inform the selection of vaccine strains. In a recent paper in the New England Journal of Read More >

Posted on by Muin J. Khoury, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a commentTags

Familial Hypercholesterolemia as a Prototype for Precision Public Health

Dr Khoury and Dr. Thompson

In October 2019, the 7th annual FH Foundation global summit on familial hypercholesterolemia (FH) took place in Atlanta, Georgia. The theme of the conference was, “Familial Hypercholesterolemia as a Prototype for Precision Public Health.” The meeting brought more than 300 participants from multiple countries to discuss the latest advances in the diagnosis, screening, treatment and Read More >

Posted on by Muin J. Khoury, Office of Public Health Genomics and Betsy L. Thompson, Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a commentTags

Introducing the CDC Office of Genomics and Precision Public Health: What’s in a Name?

Public Health Genomics changing to Genomics & Precision Public Health with a checkmark and DNA

Starting this week, the CDC Office of Public Health Genomics will be renamed the CDC Office of Genomics and Precision Public Health. In many ways, this transition has been a few years in the making and reflects the continuous broadening of our scope from human genomics and public health to include other areas relevant to Read More >

Posted on by Muin J. Khoury, Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a comment

Can Big Data Science Deliver Precision Public Health?

a big data word globe held by a person and a crowd of people with a small group being focused on

This blog is a quick summary of our recent paper in Public Health Genomics.   Increasingly, a large volume of health and non-health related data from multiple sources is becoming available that has the potential to drive health related discoveries and implementation. The term “big data” is often used as a buzzword to refer to large Read More >

Posted on by Muin J. Khoury, Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia; Michael Engelgau, George A. Mensah, Center for Translation Research and Implementation Science, National Heart, Lung, and Blood Institute, Bethesda, Maryland; David A. Chambers, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MarylandLeave a commentTags

Lack of Knowledge of Natural History of New Biomarkers: The Achilles’ Heel of Precision Health!

a doctor pointing to a tablet with an achilles' heel surrounded by images of a double helix, a microscope, a temperature scale, and pill, a stethoscope, a heart with a beat, a virus, a test tube, a medicine bag and several test tubes

In Greek mythology, when Achilles was a baby, it was foretold that he would die young. To prevent his death, his mother dipped his body in the River Styx, which was supposed to offer powers of invulnerability. However, as she held the baby by the heel, the heel did not come into contact with the Read More >

Posted on by Muin J. Khoury, Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GeorgiaLeave a commentTags