Category: precision public health
Colliding with Collider Bias: Implications for Precision Public Health
A recent JAMA Guide to Statistics and Methods reviews how collider bias can lead to erroneous inference on causal relationships in clinical and epidemiological studies, potentially leading to incorrect clinical decision making and ineffective public health action. What is Collider Bias? Informed decision making in medicine and public health relies on valid evidence from clinical Read More >
Posted on by Leave a commentPrecision Public Health in Action: Enhancing models to predict risk of adverse treatment outcomes in people with hemophilia
In collaboration with the CDC Office of Advanced Molecular Detection, the Office of Genomics and Precision Public Health recently funded the National Center on Birth Defects and Developmental Disabilities (NCBDDD) to strengthen public health capacity by introducing elements of human genomics into applied research on predicting inhibitor risk in people with hemophilia. Hemophilia refers to a group Read More >
Posted on by Leave a commentPrecision Public Health in Action: New CDC Pilot Projects Integrate Human Genomics into Public Health Surveillance and Applied Research
In collaboration with the CDC Office of Advanced Molecular Detection, we recently launched a new, five-year initiative to strengthen public health capacity by introducing elements of human genomics into both public health surveillance and applied research. We report here on the successful launch of one of the initiative’s components. The Office of Genomics and Precision Public Read More >
Posted on by Leave a commentFrom Precision Medicine to Precision Public Health: The Dialogue Continues
A recent Nature article discusses the concept of precision public health (PPH) and raises concerns that too much emphasis on data and technology is “diverting attention away from regular public health.” In this post, we advance this important dialogue by focusing on two distinct components of PPH: its role in reaping the population health benefits Read More >
Posted on by Leave a commentMendelian Randomization: A Precision Public Health Tool for the COVID-19 Response
In the early days of the COVID-19 pandemic, when little was known about the natural history of the disease, predicting the course of the pandemic was of premier importance for treating sick patients and redoubling efforts to protect those at highest risk of adverse outcomes. To address this need, investigators used a study design that Read More >
Posted on by Leave a commentApplications of Digital Tools for Precision Public Health in the COVID-19 Era: Where Are We?
Two recent systematic scoping reviews explore the use and limitations of digital tools in public health surveillance and their applications to the pandemic response Digital health tools offer increasing potential for substantial benefits to medicine and public health. In clinical practice, digital applications include personal wearable devices, devices within the body, and sensors that can Read More >
Posted on by Leave a comment2020: A Challenging Year of Progress for Genomics and Precision Public Health
It is time to wrap up an eventful 2020 which unfortunately was dominated by the COVID-19 pandemic. From January 2020 through November 2020, we saw a major increase in visits to our website (> 2.6 million views, compared to 2 million views in 2019 and 1.2 million views in 2018). In our year end blog, Read More >
Posted on by Leave a commentA Strong Start: Enhancing Newborn Screening for Precision Public Health
As the capability to sequence an individual’s genome or exome continues to expand—and the cost continues to fall—more states are considering how next generation sequencing (NGS) could support their newborn screening programs, which test approximately four million babies born in the United States each year for congenital, treatable diseases. Results from NGS can help enhance Read More >
Posted on by Leave a commentPrecision Public Health and the COVID-19 Response
This blog is a summary of our recent paper in the Journal of the American Association. The public health response to COVID-19 requires a mix of general and targeted public health interventions, i.e., precision public health. Precision public health uses data from traditional and emerging sources to target interventions for populations by person, place, and Read More >
Posted on by 1 CommentPredictive Analytics, Implementation Science, Precision Medicine and Precision Public Health
This blog is a summary of our recent paper based on a multidisciplinary workshop convened by the National Heart, Lung, and Blood Institute to explore enhancement of predictive analytics for implementation research. The use of predictive analytics in precision medicine (the right intervention to the right patient at the right time) is well established. The Read More >
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