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Selected Category: Antimicrobial Resistance

Antibiotic Resistance: Urgent Health Threat Jeopardizing Modern Medicine

Categories: Antibiotic use, Antimicrobial Resistance

Estimated minimum 2,049,442  illnesses and 23,000 deaths are caused by antibiotic resistance

Estimated minimum 2,049,442 of illnesses and 23,000 deaths are caused by antibiotic resistance

Antibiotic resistance, the ability of bacteria to resist the effects of drugs, is perhaps the single most important infectious disease threat of our time.  Although some people are at greater risk than others, no one can completely avoid the risk of antibiotic-resistant infections. These infections affect real people and they can be horrible for patients. Infections with resistant organisms are difficult to treat, requiring costly and sometimes toxic alternatives. Resistant infections account for at least $20 billion in excess direct healthcare costs and up to $35 billion in lost productivity due to hospitalizations and sick days each year.

Every year, more than two million people in the United States get infections that are resistant to antibiotics, and at least 23,000 people die as a result. Clostridium difficile (C. diff), a serious diarrheal infection usually associated with antibiotic use, causes about 250,000 hospitalizations and at least 14,000 deaths every year in the United States.

Antimicrobial Stewardship – a concept we must all embrace

Categories: Antibiotic use, Antimicrobial Resistance

Jennie L. Mayfield, BSN, MPH, CIC

Jennie L. Mayfield, BSN, MPH, CIC

Guest Author: Jennie L. Mayfield, BSN, MPH, CIC
2014 President,
Association for Professionals in Infection Control and Epidemiology (APIC)

A retrospective study from The University of Texas College of Pharmacy published in the October issue of the American Journal of Infection Control (AJIC), found that C. difficile infections (CDI) nearly doubled from 2001 to 2010 in U.S. hospitals.

Researchers analyzed 10 years of data from the U.S. National Hospital Discharge Surveys (NHDS) and found that from 2001 to 2010, rates of CDI among hospitalized adults rose from 4.5 to 8.2 CDI discharges per 1,000 total adult hospital discharges.

Antibiotic resistance: Know your ABC’s

Categories: Antibiotic use, Antimicrobial Resistance

Crystal Heishman MSN, RN, CIC, ONC

Crystal Heishman MSN, RN, CIC, ONC

Guest Author: Crystal Heishman MSN, RN, CIC, ONC
Infection preventionist at the University of Louisville Hospital

As healthcare providers and patients, we have long heard the warnings about the dangers and eminent threat of antibiotic resistance. Bacteria have continually adapted to antibiotics, becoming increasingly resistant to many of the medications used to treat them. Resistance is now a global issue that must be addressed comprehensively and quickly.

The Association for Professionals in Infection Control and Epidemiology (APIC) is raising awareness and focusing attention on antibiotic resistance during Get Smart About Antibiotics Week. The centerpiece of this outreach is a new “ABC’s of Antibiotics [PDF – 714 KB]” infographic poster for patients and families that illustrates when antibiotics work and when they don’t.

A = Ask if antibiotics are appropriate; B = Bacteria – antibiotics only kill bacteria and won’t work to treat viruses; and C = Complete the course of your medicines – even if you feel better before you finish them.

Executive Order Issued On One of the Most Urgent Health Concerns Facing Us Today

Categories: Antimicrobial Resistance, Healthcare-associated infections

Plates of plates of methicillin-resistant Staphylococcus aureus (MRSA) in CDC’s healthcare-associated infections laboratory.

Plates of plates of methicillin-resistant Staphylococcus aureus (MRSA) in CDC’s healthcare-associated infections laboratory.

National Strategy to Combat Antibiotic-Resistant Bacteria

The announcement Thursday morning of the President’s Executive Order and the National Strategy to Combat Antibiotic-Resistant Bacteria marks the administration’s response to one of the most urgent health threats facing us today – antibiotic resistance.

Read more of the original post

 

 

Success in Controlling Outbreaks in an Intensive Care Unit Using CDC Toolkit Interventions

Categories: Antimicrobial Resistance, Gram negatives, Healthcare-associated infections

Dr. Kyle Enfield

Dr. Kyle Enfield

Guest Author: Kyle B. Enfield, MD,
Assistant Professor of Medicine,
Assistant Hospital Epidemiologist,
Medical Director, Medical Intensive Care Unit,
University of Virginia

Infections due to carbapenem-resistant Enterobacteriaceae (CRE) are on the rise globally. These infections have limited therapeutic options, and invasive infections due to CRE are associated with a mortality rate upwards of 40 percent. A scary statistic for patients!

My institution, the University of Virginia Health System, identified our first case of CRE in August 2007. We had low level transmission with periods of improvement; however, in January 2010 we noted both an increase in CRE transmission among patients in the surgical intensive care unit (SICU), as well as a cluster of infections caused by a nosocomial pathogen new to the unit and our institution – extensively drug-resistant Acinetobacter baumannii (XDR-AB).

It was critical that we address this potential issue head-on in order to ensure positive patient outcomes and do our best to limit our institution’s exposure to CRE. After initial attempts to control these concurrent outbreaks of multidrug-resistant Gram negative pathogens using reinforced standard infection control practices failed, we implemented a bundled set of infection control interventions aimed to assess the prevalence of CRE and XDR-AB colonization or infection in the unit. The collective set of measures we implemented became recommended practice in the Centers for Disease Control and Prevention 2012 Carbapenem-resistant Enterobacteriaceae Toolkit. The interventions were developed by units in collaboration with Infection Prevention and Control and Environmental Services.

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